14. Kaposi's Sarcoma - Clinical/Micro
The purple-red color of the gross photograph of Kaposi's sarcoma
reiterates the microscopic features of the neoplasm, which is of
vascular origin. The photomicrograph highlights the plump spindled
cells outlining vascular spaces, which comprise the lesion. Because
this is a vascular lesion, extravasated erythrocytes are also
commonly seen. Kaposi's sarcoma has recently been associated with a
virus called Kaposi's sarcoma-associated herpes virus (KSHV). This
virus is found in virtually all of Kaposi's sarcoma, both
AIDS-associated and non-AIDS associated. The jury is still out on
whether the virus actually causes the lesion, is a co-factor, or is
merely incidental. What is the intestinal manifestation of this
disease as discussed in your text?
Answer
