5. Acute Gastric Ulcers - Gross
Acute ulcers are multiple, small, circular mucosal defects that typically measure less than 1cm. The ulcer base is stained a dark brown by the acid digestion of extruded blood. The necrosis involves the entire thickness of the mucosa. When the necrosis only involves the superficial mucosa, the lesion is an erosion. Acute gastric ulcers are usually not associated with fibrosis, which characterizes a chronic peptic ulcer. Acute, or stress, ulcers are most commonly encountered in patients with shock, burn, sepsis, intracranial conditions, and aspirin. They may be associated with lethal bleeding. Are acute gastric ulcers associated with Helicobacter pylori? Answer

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