2. Cervix, High Grade Squamous Intraepithelial Lesion (CIN III) - Medium Power
Virtually the entire thickness of the cervical epithelium is affected by dysplastic changes. Note the cellular and nuclear pleomorphism, failure of normal and orderly differentiation, hyperchromatic nuclei, and several mitotic figures extending toward the surface. Only the very superficial cells appear to differentiate and flatten. Although the basement membrane is not visible in this image, it is intact. What are the risk factors for the development of cervical dysplasia? Answer

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