Learning Objectives
Resources
Scenario
1. Systemic lupus erythematous (SLE); skin,
clinical presentation of the malar (butterfly) rash
2. Kidney; Lupus nephritis, chronic
3. Lupus nephritis - Micro, Low Power
4. Lupus nephritis - Micro, High Power
5. Lupus nephritis, wire loop lesion - Micro,
High Power
6. Lupus nephritis - Micro, High Power
7. SLE; glomerulus with immune complexes shown
by immunofluorescence ("lumpy-bumpy" fluorescence in glomerular
basement membranes)
8. Goodpasture's Disease; glomerulus with
immunofluorescence
9. SLE; chronic pleuritis with interstitial
pneumonitis and fibrosis; lungs - Gross
10. Schematic illustration of immune complex
formation, deposition and resultant injury
11. Schematic illustration of the pathogenesis
of immune complex-mediated injury. The morphologic consequences are
depicted as boxed areas.