Albumin and Plasma Protein Fraction

We stock:

• 25% albumin (concentrated, not isotonic) in 50 ml bottles
• 5% PPF (isotonic) in 250 ml bottles (sometimes 500 ml bottles) Has at least 83% albumin with alpha and beta globulins. No gamma globulins. "Plasmanate" is one brand name for PPF.
• 5% albumin (isotonic) in 250 ml bottles (sometimes 500 ml bottles), and in 50 ml bottles for pediatric use

All are meant for colloid replacement. All are pasteurized and not known to transmit infectious diseases. They are expensive, however, and not infrequently in short supply. See appendix 1 in paper supplement for indications for use.

Historically, PPF caused severe sudden hypotensive episodes in some patients. This problem was found to be due to activated Hageman factor fragments in some PPF lots. Lots are now screened to remove these, so hypotension is no longer reported as a problem.

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